The SERPING1 Antibody (CAB12407) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SERPING1 protein, this antibody allows for the detection and analysis of SERPING1 in various cell types, making it an essential reagent for studies in immunology and inflammatory diseases.SERPING1, also known as C1 inhibitor, plays a crucial role in regulating the complement system to prevent excessive inflammation and tissue damage.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SERPING1 Antibody
SKU:
CAB12407
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
C1IN, C1NH, HAE1, HAE2, C1INH, SERPING1
Positive Sample:
Mouse heart
Cellular Localization:
Secreted.
Calculated MW:
55kDa
Observed MW:
60kDa
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Purification Method
Affinity purification
Gene ID
710
RRID
AB_2759251
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from mouse heart, using SERPING1 Rabbit pAb (CAB12407) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Immunofluorescence analysis of Hep G2 cells using SERPING1 Rabbit pAb (CAB12407) at a dilution of 1:100 (40x lens). Secondary antibody:Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
