Growth Factors

system_update_altDatasheetsystem_update_altMSDSHuman EGF Recombinant Protein Epidermal growth factor (EGF) is a little 53 amino acid protein with three disulfide connections. It's a mitogenic protein that's been linked to cell development, tumour...

system_update_altDatasheetsystem_update_altMSDSPro-Neuregulin/NRG1-beta 1 Recombinant Protein Neuregulin-1 (heregulin-1/NRG1) is a neuregulin family protein. It's got four genes that encode a number of secreted or membrane-bound variants. The EGF-like...

system_update_altDatasheetsystem_update_altMSDSPro-Neuregulin/NRG1-beta 1 Recombinant Protein Neuregulin-1 (heregulin-1/NRG1) is a member of the neuregulin family, which includes four genes that generate many secreted or membrane-bound isoforms. The...

system_update_altDatasheetsystem_update_altMSDSWnt Inhibitory Factor 1/WIF1 Recombinant Protein Wnt Inhibitory Factor 1 (WIF1) is a secreted protein, which binds WNT proteins and inhibits their activities. WNT proteins are extracellular signaling...

system_update_altDatasheetsystem_update_altMSDSPro-Neuregulin/NRG1-beta 1 Recombinant Protein Pro-neuregulin-1; Neuregulin-1 beta 1 (NRG1) is a single-pass type I membrane protein in the neuregulin family. NRG1 contains 1 EGF-like and 1 Ig-like C2-type...

system_update_altDatasheetsystem_update_altMSDSMouse Sonic Hedgehog/SHH Recombinant Protein Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal...

system_update_altDatasheetsystem_update_altMSDSHuman Jagged 1/JAG1 Recombinant Protein Protein jagged-1 I, also known as Jagged-1, JAGL1, HJ1, JAG1 and CD339, is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like...

system_update_altDatasheetsystem_update_altMSDSHuman Follistatin 288/FST Recombinant Protein Follistatin 288 is a secreted glycoprotein that was first discovered in ovarian follicular fluid as a follicle-stimulating hormone inhibiting factor. Follistatin...

system_update_altDatasheetsystem_update_altMSDSMouse bNGF/Beta-NGF Recombinant Protein Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large...

system_update_altDatasheetsystem_update_altMSDSHuman VEGF-D/VEGFD Recombinant Protein Vascular endothelial growth factor D (VEGF-D) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. It is highly...

system_update_altDatasheetsystem_update_altMSDSHuman VEGF-A/VEGF121 Recombinant Protein Human VEGF121 (Vascular endothelial growth factor A (VEGFA)/ Vascular permeability factor (VPF)/VEGF) is a homodimeric, heparin-binding glycoprotein which belongs to...

system_update_altDatasheetsystem_update_altMSDSHuman Amphiregulin/AREG Recombinant Protein Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids and belongs to the amphiregulin family, which includes 1 EGF-like domain. AREG is...

system_update_altDatasheetsystem_update_altMSDSMouse NOV/CCN3 Recombinant Protein NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having...

system_update_altDatasheetsystem_update_altMSDSHuman DKK3 Recombinant Protein Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and -4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an...

system_update_altDatasheetsystem_update_altMSDSMouse Activin RIIA/ACVR2A Recombinant Protein ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein...

system_update_altDatasheetsystem_update_altMSDSHuman PDGF-BB Recombinant Protein Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family, which includes a number of other members. Platelet-derived growth factor is a...

system_update_altDatasheetsystem_update_altMSDSHuman PDGF-AA Recombinant Protein Platelet-derived growth factor subunit A (PDGFA); belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein; stored in platelet alpha-granules and released...

system_update_altDatasheetsystem_update_altMSDSHuman PDGF-AA Recombinant Protein Platelet-derived growth factor subunit A (PDGFA) belongs to the PDGF/VEGF family of growth factors. PADGFA is a secreted protein that is stored in platelet alpha-granules...

system_update_altDatasheetsystem_update_altMSDSActivin Receptor 2B/ACVR2B Recombinant Protein Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily; exert their biological actions by binding to heteromeric receptor...

system_update_altDatasheetsystem_update_altMSDSActivin Receptor 2B/ACVR2B Recombinant Protein Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily; exert their biological actions by binding to heteromeric receptor...

system_update_altDatasheetsystem_update_altMSDSHuman Activin RIIA/ACVR2A Recombinant Protein Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II...

system_update_altDatasheetsystem_update_altMSDSHuman IGF-II/IGF2 Recombinant Protein Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. This family includes...

system_update_altDatasheetsystem_update_altMSDSHuman Cyr61/CCN1 Recombinant Protein Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10 , GIG1, CYR61, CCN1 and IGFBP10,...

system_update_altDatasheetsystem_update_altMSDSHuman IGF/IGF1 Recombinant Protein Insulin-like growth factor I (IGF1) is a member of the family of insulin-like growth factors that are structurally similar to proinsulin. Proteolytic digestion of...

system_update_altDatasheetsystem_update_altMSDSHuman IGF/IGF1 Recombinant Protein Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are made by proteolytic...

system_update_altDatasheetsystem_update_altMSDSMouse DLL1/Delta Recombinant Protein Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains,  acts as a ligand for...

system_update_altDatasheetsystem_update_altMSDSHuman Follistatin/FST Recombinant Protein Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms; FST317 and...

system_update_altDatasheetsystem_update_altMSDSInhibin Beta C Chain/INHBC Recombinant Protein Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion; gonadal hormone secretion; germ...

system_update_altDatasheetsystem_update_altMSDSInhibin Beta C Chain/INHBC Recombinant Protein Inhibin beta C chain; also known as activin beta-C chain and INHBC; belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through...

system_update_altDatasheetsystem_update_altMSDSHuman TGFB1/TGF-beta 1 Recombinant Protein Transforming Growth Factor beta-1 (TGF beta-1) is a secreted protein which belongs to the TGF-beta family. TGF beta-1 is found in high amounts in bone, especially...

system_update_altDatasheetsystem_update_altMSDSHuman EG-VEGF/prokineticin Recombinant Protein EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and...

system_update_altDatasheetsystem_update_altMSDSHuman EGF Recombinant Protein EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like...

system_update_altDatasheetsystem_update_altMSDSMouse WIF1 Recombinant Protein WIF1, also known as WIF-1 and wnt inhibitory factor 1, is a secreted protein which binds WNT proteins and inhibits their activities. It contains a WNT inhibitory factor (WIF)...

system_update_altDatasheetsystem_update_altMSDSHuman VEGF-C/VEGFC Recombinant Protein Vascular Endothelial Growth Factor (VEGF)-C is a member of the VEGF family, a group of polypeptide growth factors which play key roles in the physiology and pathology...

system_update_altDatasheetsystem_update_altMSDSMouse Pleiotrophin Recombinant Protein HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also...

system_update_altDatasheetsystem_update_altMSDSHuman DLL4 Recombinant Protein Delta-like protein 4 (DLL4; Delta4); a type I membrane-bound Notch ligand; is one of five known Notch ligands in mammals and interacts predominantly with Notch 1; which has a...

system_update_altDatasheetsystem_update_altMSDSMouse Noggin/NOG Recombinant Protein Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue...

system_update_altDatasheetsystem_update_altMSDSRhesus/Canine BMP-2 Recombinant Protein BMP-2 protein plays an important role in the development of bone and cartilage, like other bone morphogenetic proteins. The hedgehog pathway, TGF beta signalling...

system_update_altDatasheetsystem_update_altMSDSHuman DLL4 Recombinant Protein Delta-like protein 4 (DLL4; Delta4); a type I membrane-bound Notch ligand; is one of five known Notch ligands in mammals and interacts predominantly with Notch 1; which has a...

system_update_altDatasheetsystem_update_altMSDSRhesus/Canine BMP-2 Recombinant Protein BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog...

system_update_altDatasheetsystem_update_altMSDSHuman CTGF/CCN2 Recombinant Protein The CTGF protein belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) family, which includes six extracellular matrix-anchored secreted proteins. CTGF causes a variety of cellular...

system_update_altDatasheetsystem_update_altMSDSHuman CTGF/CCN2 Recombinant Protein CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family; which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a...

system_update_altDatasheetsystem_update_altMSDSHuman VEGF-A/VEGF121 Recombinant Protein Human VEGF121; also known as Vascular endothelial growth factor A; VEGFA; Vascular permeability factor; VPF and VEGF; is a homodimeric; heparin-binding glycoprotein...

system_update_altDatasheetsystem_update_altMSDSMouse PDGF-BB Recombinant Protein Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal...

system_update_altDatasheetsystem_update_altMSDSPleiotrophin/PTN/HB-GAM Recombinant Protein Pleiotrophin (PTN) is an secreted, strongly heparinbinding,developmentally regulated cytokine. PTN and midkine share50% amino acid (aa) sequence identity, share...

system_update_altDatasheetsystem_update_altMSDSMouse Activin RIIA/ACVR2A Recombinant Protein ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein...

system_update_altDatasheetsystem_update_altMSDSHuman Neuregulin/NRG1-Beta 1 Recombinant Protein Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified...

system_update_altDatasheetsystem_update_altMSDSHuman Noggin/NOG Recombinant Protein Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mature Human Noggin contains an N-terminal acidic region; a...

system_update_altDatasheetsystem_update_altMSDSMouse FGF-9/FGF9 Recombinant Protein Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98%...

system_update_altDatasheetsystem_update_altMSDSHuman Noggin/NOG Recombinant Protein Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). N-terminal acidic region, a central basic heparin-binding...

system_update_altDatasheetsystem_update_altMSDSMouse FGF-2/FGFb Recombinant Protein FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and...

system_update_altDatasheetsystem_update_altMSDSHuman HGF Recombinant Protein Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. It belongs to the peptidase S1 family and Plasminogen...

system_update_altDatasheetsystem_update_altMSDSMouse SHH (C25II) Recombinant Protein Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH)...

system_update_altDatasheetsystem_update_altMSDSMouse DLL4 Recombinant Protein Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a...

system_update_altDatasheetsystem_update_altMSDSHuman Persephin/PSPN Recombinant Protein Persephin is a secreted protein, belongs to the glial cell linederived neurotrophic factor (GDNF) family of the TGF-β superfamily. It shares 38-46% amino acid...

system_update_altDatasheetsystem_update_altMSDSMouse EGF Recombinant Protein EGF is a single-pass type I membrane protein,containing 8 LDL-receptor class B repeats and 9 EGF-like domains. EGF results in cellular proliferation, differentiation, and...

system_update_altDatasheetsystem_update_altMSDSHuman HBEGF Recombinant Protein Heparin-binding EGF-like growth factor (HB-EGF) is a 12-16 kDa member of the epidermal growth factor (EGF) family. It possesses an EGF-like domain, and a heparin-binding motif...

system_update_altDatasheetsystem_update_altMSDSHuman DLL1/Delta Recombinant Protein Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains,  acts as a ligand for...

system_update_altDatasheetsystem_update_altMSDSHuman/Mouse/Rat BMP-2 Recombinant Protein Bone morphogenetic protein-2 (BMP-2) is one of the transforming growth factor-beta (TGF-beta) superfamily of proteins that regulates bone growth. BMPs are formed as...

system_update_altDatasheetsystem_update_altMSDSHuman Jagged 1/JAG1 Recombinant Protein Protein Jagged 1, also known as JAG1, JAGL1 and CD339, is a single-pass type I  membrane protein which contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is...

system_update_altDatasheetsystem_update_altMSDSHuman Jagged 1/JAG1 Recombinant Protein Protein Jagged 1, also known as JAG1, JAGL1 and CD339, is a single-pass type I  membrane protein which contains 1 DSL domain and 15 EGF-like domains...

system_update_altDatasheetsystem_update_altMSDSHuman BDNF Recombinant Protein The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing...

system_update_altDatasheetsystem_update_altMSDSHuman Neurotrophin-3/NTF3 Recombinant Protein Neurotrophin-3 (NT-3) is a neurotrophic factor that belongs to the NGF family and is structurally similar to beta-NGF, BDNF, and NT-4. The NT3 cDNA sequences a...

system_update_altDatasheetsystem_update_altMSDSRat FGF-2/FGFb Recombinant Protein FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including...

system_update_altDatasheetsystem_update_altMSDSRat VEGF-A/VEGF164 Recombinant Protein Vascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot...

system_update_altDatasheetsystem_update_altMSDSRat TGFB1/TGF-beta 1 Recombinant Protein TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the...

system_update_altDatasheetsystem_update_altMSDSHuman Beta-NGF/NGFB Recombinant Protein The precursor form of nerve growth factor (proNGF) is similarly afflicted by the cystin knot motif that includes three cystine bridges, whereas proneurotrophins and...

system_update_altDatasheetsystem_update_altMSDSHuman/Mouse/Rat BDNF Recombinant Protein Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. BDNF binds with high affinity to the TrkB kinase receptor, in addition to other...

system_update_altDatasheetsystem_update_altMSDSActivin A/INHBA Recombinant Protein Activin and inhibin are two protein complexes that have nearly opposite biological effects. TGF-β superfamily members, activins, are disulfide-linked dimeric proteins that...

system_update_altDatasheetsystem_update_altMSDSHuman/Mouse FGF-8b/FGF8B Recombinant Protein Fibroblast growth factor 8 (FGF-8) is a member of the fibroblast growth factor family. FGF-8 is found to be a growth factor required for mouse mammary carcinoma...

system_update_altDatasheetsystem_update_altMSDSHuman DKK1/Dkk Recombinant Protein Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and...