[KO Validated] DIAPH1 Rabbit Polyclonal Antibody (CAB18081)

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SKU:
CAB18081
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Synonyms:
DIA1, DRF1, DFNA1, LFHL1, SCBMS, hDIA1, mDia1, [KD Validated] DIAPH1
Research Use:
Cell Biology
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Description

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[KO Validated] DIAPH1 Antibody (CAB18081)

The [KO Validated] DIAPH1 Antibody (CAB18081) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit polyclonal antibody is validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry. It specifically targets the DIAPH1 protein, allowing for precise detection and analysis in a variety of cell types.DIAPH1 plays a critical role in cell migration, cell polarity, and cytokinesis, making it an important protein in cellular processes such as tumor invasion and metastasis.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:[KO Validated] DIAPH1 Antibody
SKU:CAB18081
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:TEEK MRRA KLAK EKAE KERL EKQQ KREQ LIDM NAEG DETG VMDS LLEA LQSG AAFR RKRG PRQA NRKA GCAV TSLL ASEL TKDD AMAA VPAK VSKN SETF PTIL EEAK ELVG RAS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DIA1, DRF1, DFNA1, LFHL1, SCBMS, hDIA1, mDia1, [KD Validated] DIAPH1
Positive Sample:293T
Cellular Localization:Cell Membrane, Cell Projection, Cytoplasm, Cytoskeleton, Ruffle Membrane.
Calculated MW:141kDa
Observed MW:150kDa

This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID1729
RRIDAB_2861875
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and DIAPH1 knockdown (KD) 293T cells, using [KD Validated] DIAPH1 Rabbit pAb (CAB18081) at 1:600 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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