The TBX6 Antibody (CAB16979) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for use in Western blot applications.TBX6 plays a crucial role in the regulation of gene expression during embryogenesis, particularly in the development of the axial skeleton and skeletal muscle. Dysregulation of TBX6 has been implicated in various congenital disorders, making it a significant target for investigation in developmental biology and genetic studies.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TBX6 Antibody
SKU:
CAB16979
Size:
20μL, 100μL
Reactivity:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SCDO5, TBX6
Positive Sample:
HeLa, A-549
Cellular Localization:
Nucleus.
Calculated MW:
47kDa
Observed MW:
47kDa
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures.
Purification Method
Affinity purification
Gene ID
6911
RRID
AB_2772543
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using TBX6 Rabbit pAb (CAB16979) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
