The SRSF4 Antibody (CAB6978) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the SRSF4 protein, this antibody enables the detection and analysis of SRSF4 levels in a variety of cell types, making it well-suited for studies in molecular biology and cancer research.SRSF4 is known to play a crucial role in alternative splicing, a process that determines the diversity of mRNA transcripts and therefore the proteins produced by a cell.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
SRSF4 Antibody
SKU:
CAB6978
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SFRS4, SRP75, SRSF4
Positive Sample:
Mouse liver, Rat uterus, Rat thymus
Cellular Localization:
Nucleus Speckle.
Calculated MW:
57kDa
Observed MW:
57kDa
Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome; acute myeloid leukemia; clear cell renal cell carcinoma; and colon adenocarcinoma.
Purification Method
Affinity purification
Gene ID
6429
RRID
AB_2767534
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using SRSF4 Rabbit pAb (CAB6978) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
