Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
54.5 kDa
AP Mol Mass:
72 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM NaAc-HAc,150mM NaCl,10%Glycerol,pH4.5.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
system_update_altDatasheetHuman Prolylcarboxypeptidase (PRCP) ELISA KitThe Human Prolylcarboxypeptidase (PRCP) ELISA Kit is a highly sensitive and specific assay designed for
system_update_altDatasheetRat Prolylcarboxypeptidase (PRCP) ELISA KitThe Rat Prolylcarboxypeptidase (PRCP) ELISA Kit is a powerful tool for accurately measuring levels of PRCP
