Description
| Product Name: | Recombinant Human FGL1 (C-Avi-6His) Biotinylated |
| Product Code: | RPES6208 |
| Size: | 20µg |
| Species: | Human |
| Expression Host: | HEK293 Cells |
| Synonyms: | Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1 |
| Mol Mass: | 36.6 kDa |
| AP Mol Mass: | 35 kDa |
| Tag: | C-Avi-6His |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Bio Activity: | Immobilized Human LAG-3-Fc at 10μg/ml (100 μl/well) can bind Biotinylated Human FGL1-Avi. The ED50 of Human FGL1-Avi is 1908ng/mL. |
| Sequence: | Leu23-Ile312 |
| Accession: | Q08830 |
| Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation: | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer infor |
| Reconstitution: | Not Applicable |
| Background: | Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3. |
