Immunology

// system_update_altDatasheetHuman IDE/Insulysin Recombinant Protein Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary...

// system_update_altDatasheetMouse IFNG Recombinant Protein (E.coli) Mouse Ifng is a secreted protein which belongs to the type I I (or gamma) interferon family. IFNG is produced by lymphocytes and activated by specific antigens or mitogens. In addition...

// system_update_altDatasheetHuman Tetherin/BST2 Recombinant Protein Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver; lung; heart and...

// system_update_altDatasheetHuman TRIM5/RNF88 Recombinant Protein Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type...

// system_update_altDatasheetHuman IDO1/IDO Recombinant Protein Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This...

// system_update_altDatasheetHuman KPNB1 Recombinant Protein Importin subunit beta-1(KPNB1) is a member of the importin beta family. KPNB1 contains 1 importin N-terminal domain and 19 HEAT repeats. It is involved in nucleocytoplasmic transport, a signal-...

// system_update_altDatasheetMouse IDO1/IDO Recombinant Protein Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This...

// system_update_altDatasheetHuman JAM-A/F11R Recombinant Protein Junctional Adhesion Molecule A (JAM-A) is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. JAM-A contains 2 Ig-like V-type (immunoglobulin-like)...

// system_update_altDatasheetHuman TFIIB/GTF2B Recombinant Protein Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II. TFIIB localizes to the nucleus where it forms a complex (the DAB complex) with...

// system_update_altDatasheetIDO1/IDO Recombinant Protein (Gly&Ala2-Gly403) Indoleamine 2,3-dioxygenase-1 (Indoleamine-pyrrole 2,3-dioxygenase/IDO1/IDO) is a member of the indoleamine 2,3-dioxygenase family. IDO1 / IDO and tryptophan 2,3-dioxygenase...

// system_update_altDatasheetHuman WWP2 Recombinant Protein WWP2 contains 1 C2 domain, 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain and 4 WW domains. It is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating...

// system_update_altDatasheetHuman IFNA4 Recombinant Protein Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the...

// system_update_altDatasheetRat TIMP/TIMP1 Recombinant Protein TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of...

// system_update_altDatasheetHuman B7-H4/VTCN1 Recombinant Protein V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type? membrane protein belonging to the B7 family of costimulatory...

// system_update_altDatasheetHuman Arginase/ARG1 Recombinant Protein Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this...

// system_update_altDatasheetHuman IL10RB/IL10R2 Recombinant Protein Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the...

// system_update_altDatasheetHuman ICOS Ligand/ICOSL Recombinant Protein Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein...

// system_update_altDatasheetHuman ILRL2 Recombinant Protein Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene; belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A; IL36B and...

// system_update_altDatasheetHuman ILRL2 Recombinant Protein Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene; belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A; IL36B and...

// system_update_altDatasheetHuman ILRAcP/IL1R3 Recombinant Protein Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long...

// system_update_altDatasheetHuman IgG1 Fc Recombinant Protein Immunoglobulin G (IgG) is a monomeric immunoglobulin that is involved in the secondary antibody response and the only isotype that may pass through the human placenta, and it is produced and...

// system_update_altDatasheetComplement Factor H/CFH Recombinant Protein Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver...

// system_update_altDatasheetComplement Factor B/CFB Recombinant Protein Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC)...

// system_update_altDatasheetHuman C8G Recombinant Protein Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a...

// system_update_altDatasheetComplement Component C3a/C3a Recombinant Protein The complement system is an important component of natural immunity and the first line of defense in the battle against invading organisms. Complement 3 (C3) is the most common...

// system_update_altDatasheetHuman Collectin1/COLEC11 Recombinant Protein Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play...

// system_update_altDatasheetHuman HMGB3 Recombinant Protein High Mobility Group Protein B3 (HMGB3) belongs to the HMGB family. Members of the HMG box subfamily are thought to be have an important role in DNA replication, nucleosome assembly and...

// system_update_altDatasheetHuman HMGB1 Recombinant Protein High mobility group protein B1 is a member of the HMGB family consisting of three members; HMGB1; HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a...

// system_update_altDatasheetHuman CLEC4E/Mincel Recombinant Protein C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E...

// system_update_altDatasheetMouse Serpin A3N Recombinant Protein Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to ?1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in...

// system_update_altDatasheetHuman ULBP2/N2DL-2 Recombinant Protein NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a...

// system_update_altDatasheetHuman ULBP2/N2DL-2 Recombinant Protein NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a...

// system_update_altDatasheetHuman NKG2DL/ULBP Recombinant Protein NKG2D ligand 1; also called ULBP1; is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical...

// system_update_altDatasheetHuman NKG2DL/ULBP Recombinant Protein ULBP1; also known as RAET1I and NKG2DL1; is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses; especially in cancer and infectious diseases; and is...

// system_update_altDatasheetHuman TRIM/TRAT1 Recombinant Protein T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus,...

// system_update_altDatasheetHuman NPM1/Nucleophosmin Recombinant Protein Nucleophosmin 1 (NPM1), also known as nucleolar phosphoprotein B23 or numatrin, is a member of the nucleoplasmin family. Nucleophosmin (NPM) is a nucleolar phosphoprotein that...

// system_update_altDatasheetHuman TIM-3/HAVCR2 Recombinant Protein Hepatitis A virus cellular receptor 2?HAVCR2?is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the...

// system_update_altDatasheetMouse CTLA4 Recombinant Protein Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to...

// system_update_altDatasheetMouse CTLA4 Recombinant Protein Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence, a 126 aa...

// system_update_altDatasheetMouse CTLA4 Recombinant Protein Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to...

// system_update_altDatasheetHuman NFkB p65 Recombinant Protein RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth...

// system_update_altDatasheetBCL6/B-cell CLL lymphoma 6 Recombinant Protein The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported...

// system_update_altDatasheetPre-Haptoglobin-2/Zonulin Recombinant Protein Haptoglobin(HP) is a secreted protein which is a member of the peptidase S1 family of serine proteases. As a result of hemolysis; hemoglobin is found to accumulate in the kidney...

// system_update_altDatasheetHuman ULBP2/N2DL-2 Recombinant Protein NKG2D ligand 2; also known as N2DL-2; NKG2DL2; ALCAN-alpha; Retinoic acid early transcript 1H; UL16-binding protein 2; ULBP2 and N2DL2; is cell membrane protein which belongs to...

// system_update_altDatasheetHuman Haptoglobin/Zonulin Recombinant Protein Haptoglobin(HP) is a secreted protein which is a member of the peptidase S1 family of serine proteases. As a result of hemolysis; hemoglobin is found to accumulate in the kidney...

// system_update_altDatasheetHuman GRB2 Recombinant Protein As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with...

// system_update_altDatasheetHuman CTLA4 Recombinant Protein Cytotoxic T-lymphocyte protein 4; is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4; together with their ligands; B7-1...

// system_update_altDatasheetMouse Complement C3a Recombinant Protein Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the...

// system_update_altDatasheetHuman EGFR/ErbB1 Recombinant Protein The EGFR subfamily of receptor tyrosine kinases is composed of EGFR; ErbB2; ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these...

// system_update_altDatasheetHuman Tetherin/BST2 Recombinant Protein CLM-9; also known as TREM4; is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including...

// system_update_altDatasheetHuman NCR3/NKp30 Recombinant Protein Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering...

// system_update_altDatasheetHuman PLA2G16 Recombinant Protein Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in...