Immune Checkpoint Proteins

system_update_altDatasheetsystem_update_altMSDSMouse CTLA4/CD152 Recombinant Protein Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the...

system_update_altDatasheetsystem_update_altMSDSMouse ICOS Ligand/ICOSL Recombinant Protein Mouse ICOS ligand(B7-H2) is an approximately transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is expressed on antigen presenting...

system_update_altDatasheetsystem_update_altMSDSHuman PD-L1/B7-H1/CD274 Recombinant Protein CD274; also known as B7-H1 or programmed death ligand 1 (PD-L1); is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin...

system_update_altDatasheetsystem_update_altMSDSHuman PD-L1/B7-H1/CD274 Recombinant Protein CD274; also known as B7-H1 or programmed death ligand 1 (PD-L1); is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin...

system_update_altDatasheetsystem_update_altMSDSHuman PD-L1/B7-H1/CD274 Recombinant Protein CD274; also known as B7-H1 or programmed death ligand 1 (PD-L1); is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin...

system_update_altDatasheetsystem_update_altMSDSRat CD86/B7-2 Recombinant Protein CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a...

system_update_altDatasheetsystem_update_altMSDSHuman PDCD10/TFAR15 Recombinant Protein The programmed cell death protein 10 (PDCD10) family includes PDCD10. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated...

system_update_altDatasheetsystem_update_altMSDSHuman CD80/B7 Recombinant Protein B7-1 (CD80) is a cell surface immunoglobulin superfamily member that is expressed on the surfaces of antigen presenting cells such as activated B cells, macrophages, and...

system_update_altDatasheetsystem_update_altMSDSHuman PD/PDCD1 Recombinant Protein Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of...

system_update_altDatasheetsystem_update_altMSDSHuman PD/PDCD1 Recombinant Protein Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of...

system_update_altDatasheetsystem_update_altMSDSHuman PD/PDCD1 Recombinant Protein Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of...

system_update_altDatasheetsystem_update_altMSDSMouse TIGIT Recombinant Protein TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein...

system_update_altDatasheetsystem_update_altMSDSHuman B7-H6 Recombinant Protein Natural cytotoxicity triggering receptor 3 ligand 1(B7-H6) is a glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H6 consists of a 238...

system_update_altDatasheetsystem_update_altMSDSHuman LAG3/CD223 Recombinant Protein Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8...

system_update_altDatasheetsystem_update_altMSDSHuman CGB7 Recombinant Protein CGB7 (chorionic gonadotropin, beta polypeptide 7) belongs to the glycoprotein hormones subunit beta family. Glycoprotein hormones are heterodimers consisting of a common alpha...

system_update_altDatasheetsystem_update_altMSDSHuman B7-H4/VTCN1 Recombinant Protein V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type? membrane protein belonging to the B7 family of...

system_update_altDatasheetsystem_update_altMSDSHuman LAG3/CD223 Recombinant Protein Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8...

system_update_altDatasheetsystem_update_altMSDSHuman LAG3/CD223 Recombinant Protein Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8...

system_update_altDatasheetsystem_update_altMSDSHuman ICOS Ligand/ICOSL Recombinant Protein Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a...

system_update_altDatasheetsystem_update_altMSDSHuman LAG3/CD223 Recombinant Protein Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8...

system_update_altDatasheetsystem_update_altMSDSHuman ICOS Ligand/ICOSL Recombinant Protein Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a...

system_update_altDatasheetsystem_update_altMSDSMouse HSPD1/HSP60 Recombinant Protein HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for...

system_update_altDatasheetsystem_update_altMSDSMouse B7-DC/PD-L2/CD273 Recombinant Protein Programmed cell death 1 ligand 2 (PD-L2), also known as butyrophilin B7-DC or PDCD1 ligand 2, belongs to the member of B7 family which can regulate the activation...

system_update_altDatasheetsystem_update_altMSDSMouse PD/PDCD1 Recombinant Protein Programmed Death-1 (PD-1), firstly cloned from mouse T cell hybridoma 2B4.11, is one member of CD28/CTLA-4 superfamily. PD-1 belongs to type I transmembrane protein and...

system_update_altDatasheetsystem_update_altMSDSMouse PD/PDCD1 Recombinant Protein Programmed Death-1 (PD-1), firstly cloned from mouse T cell hybridoma 2B4.11, is one member of CD28/CTLA-4 superfamily. PD-1 belongs to type I transmembrane protein and...

system_update_altDatasheetsystem_update_altMSDSMouse PD-L1/B7-H1/CD274 Recombinant Protein Mouse Programmed cell death 1 ligand 1(Cd274?PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for...

system_update_altDatasheetsystem_update_altMSDSMouse TIM-3/HAVCR2 Recombinant Protein T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune...

system_update_altDatasheetsystem_update_altMSDSMouse TIM-3/HAVCR2 Recombinant Protein T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune...

system_update_altDatasheetsystem_update_altMSDSMouse TIGIT Recombinant Protein T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called WUCAM, VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT...

system_update_altDatasheetsystem_update_altMSDSMouse CD28/TP44 Recombinant Protein T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which...

system_update_altDatasheetsystem_update_altMSDSMouse CD86/B7-2 Recombinant Protein CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a...

system_update_altDatasheetsystem_update_altMSDSMouse CD86/B7-2 Recombinant Protein T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important...

system_update_altDatasheetsystem_update_altMSDSHuman B7-H5/Gi24/VSIR Recombinant Protein platelet receptor Gi24 is a single-pass type I membrane protein; and located at the cell surface. The protein can be cleaved by MMP14; and stimulate MMP14-mediated...

system_update_altDatasheetsystem_update_altMSDSHuman TIM-3/HAVCR2 Recombinant Protein Hepatitis A virus cellular receptor 2?HAVCR2?is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs...

system_update_altDatasheetsystem_update_altMSDSRat CD80/B7 Recombinant Protein Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells...

system_update_altDatasheetsystem_update_altMSDSHuman PD-L1/B7-H1/CD274 Recombinant Protein Programmed death-1 ligand-1 (PD-L1; CD274; B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been...

system_update_altDatasheetsystem_update_altMSDSMouse CTLA4 Recombinant Protein Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human...

system_update_altDatasheetsystem_update_altMSDSMouse CTLA4 Recombinant Protein Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal...

system_update_altDatasheetsystem_update_altMSDSHuman HSPB7 Recombinant Protein PSG2 is a secreted protein that in humans is encoded by the PSG2 gene. It is a member of the human pregnancy-specific glycoproteins (PSGs) family. These proteins are...

system_update_altDatasheetsystem_update_altMSDSHuman PD-L1/B7-H1/CD274 Recombinant Protein CD274; also known as B7-H1 or programmed death ligand 1 (PD-L1); is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin...

system_update_altDatasheetsystem_update_altMSDSMouse CTLA4 Recombinant Protein Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human...

system_update_altDatasheetsystem_update_altMSDSHuman PD-L2/CD273 Recombinant Protein Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is...

system_update_altDatasheetsystem_update_altMSDSHuman PD/PDCD1 Recombinant Protein Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of...

system_update_altDatasheetsystem_update_altMSDSMouse PD-L1/B7-H1/CD274 Recombinant Protein Mouse Programmed cell death 1 ligand 1(Cd274,PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for...

system_update_altDatasheetsystem_update_altMSDSMouse PD-L1/B7-H1/CD274 Recombinant Protein Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been...

system_update_altDatasheetsystem_update_altMSDSMouse B7-H4/VTCN1 Recombinant Protein V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type? membrane protein belonging to the B7 family of...

system_update_altDatasheetsystem_update_altMSDSHuman CTLA4 Recombinant Protein Cytotoxic T-lymphocyte protein 4; is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4; together with...

system_update_altDatasheetsystem_update_altMSDSMouse CD80/B7 Recombinant Protein Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells...