PKD2 Rabbit Polyclonal Antibody (CAB3625)

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SKU:
CAB3625
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
PC2, PKD4, Pc-2, APKD2, TRPP2, PKD2
Research Use:
Cell Biology
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Description

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PKD2 Antibody (CAB3625)

The PKD2 Antibody (CAB3625) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in various applications, including Western blotting.Polycystin-2 is a calcium-permeable cation channel that is primarily expressed in the kidneys and is involved in the regulation of calcium signaling and fluid flow in renal tubules.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PKD2 Antibody
SKU:CAB3625
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:EVLG RLLD GVAE DERL GRDS EIHR EQME RLVR EELE RWES DDAA SQIS HGLG TPVG LNGQ PRPR SSRP SSSQ STEG MEGA GGNG SSNV HV
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PC2, PKD4, Pc-2, APKD2, TRPP2, PKD2
Positive Sample:293T, MCF7, Mouse kidney
Cellular Localization:Cell Projection, Endoplasmic Reticulum, Multi-Pass Membrane Protein, Cilium Membrane.
Calculated MW:110kDa
Observed MW:110kDa

This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

Purification MethodAffinity purification
Gene ID5311
RRIDAB_2765186
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PKD2 Rabbit pAb (CAB3625) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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