The OLR1 Antibody (CAB1639) is a high-quality antibody developed for reliable detection and analysis of target proteins. This cell surface receptor is involved in lipid metabolism, inflammation, and atherosclerosis, making it a key target in cardiovascular research.Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the OLR1 protein, allowing for accurate detection and analysis in a variety of cell types. This makes it an ideal choice for studies in cardiovascular disease, lipid metabolism, and related research areas.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
OLR1 Antibody
SKU:
CAB1639
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LOX1, LOXIN, SLOX1, CLEC8A, SCARE1, OLR1
Positive Sample:
HepG2, SH-SY5Y, Mouse liver
Cellular Localization:
Cell Membrane, Lipid-Anchor, Membrane Raft, Secreted, Single-Pass Type Ii Membrane Protein.
Calculated MW:
31kDa
Observed MW:
31kDa
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
4973
RRID
AB_2763697
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using OLR1 Rabbit pAb (CAB1639) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
