MPI Rabbit Polyclonal Antibody (CAB7319)

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SKU:
CAB7319
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
PMI, PMI1, CDG1B, MPI
Research Use:
Cell Biology
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Description

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MPI Antibody (CAB7319)

The MPI Antibody (CAB7319) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.The MPI protein plays a crucial role in maintaining proper levels of vitamin B6, which is essential for various biological processes such as amino acid metabolism, neurotransmitter synthesis, and immune function. Dysregulation of MPI and vitamin B6 metabolism has been implicated in a range of diseases, including certain cancers, neurological disorders, and cardiovascular diseases.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MPI Antibody
SKU:CAB7319
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAAP RVFP LSCA VQQY AWGK MGSN SEVA RLLA SSDP LAQI AEDK PYAE LWMG THPR GDAK ILDN RISQ KTLS QWIA ENQD SLGS KVKD TFNG NLPF LFKV LSVE TPLS IQAH PNKE LAEK LHLQ APQH YPDA NHKP EMAI ALTP FQGL CGFR PVEE IVTF LKKV PEFQ FLIG DEAA THLK QTMS HDSQ AVAS SLQS CFSH LMKS EKKV VVEQ LNLL VKRI SQQA AAGN NMED IFGE LLLQ LHQQ YPGD IGCF AIYF LNLL TLKP GEAM FLEA NVPH AYLK GDCV ECMA CSDN TVRA GLTP KFID VPTL CEML SYTP SSSK DRLF LPTR SQED PYLS IYDP PVPD FTIM KTEV PGSV TEYK VLAL DSAS ILLM VQGT VIAS TPTT QTPI PLQR GGVL FIGA NESV SLKL TEPK DLLI FRAC CLL
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PMI, PMI1, CDG1B, MPI
Positive Sample:Jurkat, HepG2, HeLa, SW620, Mouse heart
Cellular Localization:Cytoplasm.
Calculated MW:47kDa
Observed MW:47kDa

Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID4351
RRIDAB_2767859
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using MPI Rabbit pAb (CAB7319) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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