[KO Validated] SMARCC1/BAF155 Rabbit Polyclonal Antibody (CAB6128)

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SKU:
CAB6128
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
Synonyms:
HYC5, Rsc8, SRG3, SWI3, BAF155, CRACC1, 55
Research Use:
Neuroscience
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Description

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[KO Validated] SMARCC1/BAF155 Antibody (CAB6128)

The [KO Validated] SMARCC1/BAF155 Antibody (CAB6128) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications.SMARCC1 plays a crucial role in controlling chromatin structure and gene transcription, influencing key cellular processes such as differentiation, proliferation, and DNA damage response. Dysregulation of SMARCC1 expression has been linked to various diseases, including cancer and developmental disorders.

This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:[KO Validated] SMARCC1/BAF155 Antibody
SKU:CAB6128
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LVVQ LLQF QEDA FGKH VTNP AFTK LPAK CFMD FKAG GALC HILG AAYK YKNE QGWR RFDL QNPS RMDR NVEM FMNI EKTL VQNN CLTR PNIY LIPD IDLK LANK LKDI IKRH QGTF TDEK SKAS HHIY PYSS SQDD EEWL RPVM RKEK QVLV HWGF YPDS YDTW VHSN DVDA EIED PPIP EKPW KVHV KWIL DTDI FNEW MNEE DYEV DENR KPVS FRQR ISTK NEEP VRSP ERRD RKAS A
Tested Applications:WB IP ELISA
Recommended Dilution:
WB1:500 - 1:1000
IP0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HYC5, Rsc8, SRG3, SWI3, BAF155, CRACC1, 55
Positive Sample:293T
Cellular Localization:Nucleus.
Calculated MW:123kDa
Observed MW:155kDa

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.

Purification MethodAffinity purification
Gene ID6599
RRIDAB_2863524
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and SMARCC1/BAF155 knockout (KO) 293T cells, using [KO Validated] SMARCC1/BAF155 Rabbit pAb (CAB6128) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunoprecipitation analysis of 200 μg extracts of 293T cells using 1 μg SMARCC1/BAF155 antibody (CAB6128). Western blot was performed from the immunoprecipitate using SMARCC1/BAF155 antibody (CAB6128) at a dilution of 1:1000.
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