Iscalimab ELISA Kit (GXEL00164)

Iscalimab ELISA Kit

The Iscalimab ELISA Kit (SKU: GXEL00164) enables sensitive, reproducible quantitative detection of Iscalimab in Plasma, Serum using a quantitative ELISA format. The assay delivers a detection range of 0.31-5 μg/mL and a sensitivity of 0.156 μg/ml and is read colorimetrically at 450 nm, making it well suited to quantitative research workflows.

Iscalimab is a new, fully human, monoclonal antibody preventing cluster of differentiation 40 (CD40) pathway signaling and activation of CD40+ cell types. In a recent multicenter, randomized control trial (NCT02217410), with the primary endpoint of non-inferiority on the composite endpoint, iscalimab therapy showed non-inferiority on a composite clinical endpoint, improved renal function, reduced risk for new onset diabetes and similar safety compared with tacrolimus. The analysis presented at the ATC included patients from this study that underwent either routine biopsies or biopsies as part of a follow-up protocol. The data was reviewed and scored by a blinded pathologist using the established Banff criteria and CADI. A CADI of 1 or less was considered as 'normal renal histology'. The average CADI at final biopsy was 1.6 ±0.6 for iscalimab and 5.1 ±0.8 for tacrolimus.

Supplied with pre-coated microplates and all core reagents, the Iscalimab ELISA Kit gives you a validated, ready-to-use solution for Iscalimab research. Get accurate and reliable results with the Iscalimab ELISA Kit from Assay Genie.