Description
| Product name | Human F2RL1 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP018 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | F2RL1 |
| Uniprot: | P55085 |
| Description: | Human F2RL1 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length F2RL1 protein has a MW of 44.1 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | Neuroactive ligand-receptor interaction |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | GPR11; PAR2 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | A member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. |
| Delivery: | In Stock |
| Usage | Research use only |
