Description
| Product name | Human CX3CR1 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP096 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | CX3CR1 |
| Uniprot: | P49238 |
| Description: | Human CX3CR1 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length CX3CR1 protein has a MW of 40.8 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
