The GLO1 Monoclonal Antibody (CAB4329) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit monoclonal cells, is highly specific and reactive with human samples, making it ideal for various research applications.GLO1 is a key enzyme in the glyoxalase system, responsible for detoxifying methylglyoxal, a toxic byproduct of glycolysis. Dysregulation of GLO1 has been implicated in various diseases, including diabetes, neurodegenerative disorders, and cancer. By targeting GLO1 with this antibody, researchers can investigate its role in these pathologies and potentially develop new therapeutic strategies.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GLO1 Monoclonal Antibody
SKU:
CAB4329
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0969
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
Purification Method
Affinity purification
Gene ID
2739
RRID
AB_2863235
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using GLO1 Rabbit mAb (CAB4329) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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