Description
Gevokizumab ELISA Kit
The Gevokizumab ELISA Kit (SKU: GXEL00049) is a quantitative sandwich ELISA designed for the accurate quantitative detection of Gevokizumab across Plasma, Serum. With a working range of 0.31-5 μg/mL and a sensitivity of 0.156 μg/ml, the kit combines a simple protocol with dependable colorimetric read-out for confident quantification.
Gevokizumab (XOMA-052) was developed by XOMA Ltd., USA and represents a humanized IgG2kappa antibody. XOMA-052 binds to IL-1β with high affinity leading to reduced binding affinity of the cytokine to its signaling receptor. Since gevokizumab does not influence the affinity of IL-1β for its decoy and soluble inhibitory receptors the endogenous regulatory mechanisms involving the clearance and inhibitory receptors also contribute to the effect of the antibody [6]. In August 2012 the FDA granted orphan drug status to gevokizumab for the treatment of noninfectious intermediate uveitis, posterior uveitis, panuveitis, and chronic noninfectious anterior uveitis. A single intravenous injection of the substance was also shown to lead to complete resolution of intraocular inflammation in Behçet’s uveitis.
Backed by Assay Genie quality control and technical support, this Gevokizumab ELISA Kit is an ideal tool for laboratories studying Gevokizumab. Order the Gevokizumab ELISA Kit from Assay Genie for dependable performance.
| Product Name: | Gevokizumab ELISA Kit |
| SKU: | GXEL00049 |
| Accession: | P01584 |
| Alternative Names: | XOMA 052, 1129435-60-4 |
| Assay Type: | Quantitative |
| Detection Method: | Colorimetric |
| Sensitivity: | 0.156 μg/ml |
| Range: | 0.31-5 μg/mL |
| Sample Type: | Plasma, Serum |
| Storage: | 2-8°C. See Storage & Stability for details. |
| Note: | For Research Use Only. Not for diagnostic procedures. |
| Parameter | Specification |
|---|---|
| Assay Type | Quantitative |
| Detection Method | Colorimetric |
| Sensitivity | 0.156 μg/ml |
| Detection Range | 0.31-5 μg/mL |
| Recovery | 80-120% |
| Sample Types | Plasma, Serum |
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Store the kit at 2-8°C on receipt. Avoid repeated freeze-thaw cycles.
