ETV6 Rabbit Polyclonal Antibody (CAB15668)

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SKU:
CAB15668
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
TEL, THC5, TEL/ABL, ETV6
Research Use:
Epigenetics and Nuclear Signaling
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Description

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ETV6 Antibody (CAB15668)

The ETV6 Antibody (CAB15668) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ETV6 protein, this antibody enables the detection and analysis of ETV6 in various cell types, making it ideal for investigations in oncology and hematological disorders.ETV6 is a transcription factor with important roles in hematopoiesis and development.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:ETV6 Antibody
SKU:CAB15668
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSET PAQC SIKQ ERIS YTPP ESPV PSYA SSTP LHVP VPRA LRME EDSI RLPA HLRL QPIY WSRD DVAQ WLKW AENE FSLR PIDS NTFE MNGK ALLL LTKE DFRY RSPH SGDV LYEL LQHI LKQR KPRI LFSP FFHP GNSI HTQP EVIL HQNH EEDN CVQR TPRP SVDN VHHN PPTI ELLH RSRS PITT NHRP SPDP EQRP LRSP LDNM IRRL SPAE RAQG PRPH QENN HQES YPLS VSPM ENNH CPAS SESH PKPS SPRQ ESTR VIQL MPSP IMHP LILN PRHS VDFK QSRL SEDG LHRE
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:TEL, THC5, TEL/ABL, ETV6
Positive Sample:HepG2, Mouse lung, Mouse spleen, Rat testis
Cellular Localization:Nucleus.
Calculated MW:53kDa
Observed MW:55kDa

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Purification MethodAffinity purification
Gene ID2120
RRIDAB_2763076
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ETV6 Rabbit pAb (CAB15668) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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