The COMP Monoclonal Antibody (CAB22260) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, produced using cutting-edge technology, is highly specific and sensitive for detecting COMP in various sample types. Its compatibility with techniques like immunohistochemistry and ELISA makes it versatile for a wide range of research applications in orthopedics, rheumatology, and musculoskeletal biology.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
COMP Monoclonal Antibody
SKU:
CAB22260
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Clone Number:
ARC54617
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Purification Method
Affinity purification
Gene ID
1311
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using COMP Rabbit mAb (CAB22260) at 1:5000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): Mouse liver, Rat liver. Exposure time: 90 s.
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