CBR1 Rabbit Polyclonal Antibody (CAB5446)

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SKU:
CAB5446
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
CBR, hCBR1, PG-9-KR, SDR21C1, CBR1
Research Use:
Cell Biology
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Description

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CBR1 Antibody (CAB5446)

The CBR1 Antibody (CAB5446) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody exhibits high specificity and reactivity with human samples, making it an excellent choice for Western blot applications. By targeting the CBR1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in pharmacology, toxicology, and drug metabolism research.CBR1, also known as carbonyl reductase 1, plays a crucial role in the metabolism and detoxification of a wide range of endogenous and xenobiotic substrates, including drugs, steroids, and carcinogens.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:CBR1 Antibody
SKU:CAB5446
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSSG IHVA LVTG GNKG IGLA IVRD LCRL FSGD VVLT ARDV TRGQ AAVQ QLQA EGLS PRFH QLDI DDLQ SIRA LRDF LRKE YGGL DVLV NNAG IAFK VADP TPFH IQAE VTMK TNFF GTRD VCTE LLPL IKPQ GRVV NVSS IMSV RALK SCSP ELQQ KFRS ETIT EEEL VGLM NKFV EDTK KGVH QKEG WPSS AYGV TKIG VTVL SRIH ARKL SEQR KGDK ILLN ACCP GWVR TDMA GPKA TKSP EEGA ETPV YLAL LPPD AEGP HGQF VSEK RVEQ W
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CBR, hCBR1, PG-9-KR, SDR21C1, CBR1
Positive Sample:SW480, 22Rv1, MCF7, NCI-H460, SKOV3, Mouse kidney, Mouse liver, Mouse lung, Mouse testis
Cellular Localization:Cytoplasm.
Calculated MW:30kDa
Observed MW:35kDa

The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.

Purification MethodAffinity purification
Gene ID873
RRIDAB_2766248
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CBR1 Rabbit pAb (CAB5446) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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