Description
Bimagrumab ELISA Kit
The Bimagrumab ELISA Kit (SKU: GXEL00168) enables sensitive, reproducible quantitative detection of Bimagrumab in Plasma, Serum using a quantitative ELISA format. The assay delivers a detection range of 125 - 4, 000 ng/mL and a sensitivity of 97.28 ng/mL and is read colorimetrically at 450 nm, making it well suited to quantitative research workflows.
Bimagrumab is a monoclonal anti-ActRIIA/IIB antibody that targets ActRIIA and ActRIIB simultaneously. Native ActRIIA and ActRIIB are both mediators of signaling from several TGFβ superfamily members such as activins, myostatin, and GDF11. Hence, pan-blockade by Bimagrumab achieves greater effect than a monoclonal antibody against either receptor alone, i.e. monotherapy with anti-ActRIIA antibody or anti-ActRIIB antibody. Bimagrumab has been explored as a therapy for sporadic inclusion body myositis, primary sarcopenia, and muscle wasting associated with chronic obstructive pulmonary disease.
Supplied with pre-coated microplates and all core reagents, the Bimagrumab ELISA Kit gives you a validated, ready-to-use solution for Bimagrumab research. Get accurate and reliable results with the Bimagrumab ELISA Kit from Assay Genie.
| Product Name: | Bimagrumab ELISA Kit |
| SKU: | GXEL00168 |
| Accession: | P27037 & Q13705 |
| Alternative Names: | BYM338, 1356922-05-8 |
| Assay Type: | Quantitative |
| Detection Method: | Colorimetric |
| Sensitivity: | 97.28 ng/mL |
| Range: | 125 - 4, 000 ng/mL |
| Sample Type: | Plasma, Serum |
| Storage: | 2-8°C. See Storage & Stability for details. |
| Note: | For Research Use Only. Not for diagnostic procedures. |
| Parameter | Specification |
|---|---|
| Assay Type | Quantitative |
| Detection Method | Colorimetric |
| Sensitivity | 97.28 ng/mL |
| Detection Range | 125 - 4, 000 ng/mL |
| Recovery | 80-120% |
| Sample Types | Plasma, Serum |
When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20 °C, the rest reagents should be store at 4°C.
Store the kit at 2-8°C on receipt. Avoid repeated freeze-thaw cycles.
