The BDNF Antibody (CAB1307) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to BDNF in human samples and is validated for use in Western blot applications. By binding to the BDNF protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in neuroscience and neurodegenerative diseases.BDNF is a crucial factor in promoting neuronal survival, growth, and function in the brain, making it a central focus in understanding conditions such as Alzheimer's disease, depression, and neurodevelopmental disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
BDNF Antibody
SKU:
CAB1307
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ANON2, BULN2, BDNF
Positive Sample:
SH-SY5Y, U-87 MG
Cellular Localization:
Secreted.
Calculated MW:
28kDa
Observed MW:
40kDa
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Purification Method
Affinity purification
Gene ID
627
RRID
AB_2759918
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using BDNF Rabbit pAb (CAB1307) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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