Anti-TACC3 Antibody (CAB19617)
- SKU:
- CAB19617
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ERIC-1
- Synonyms:
- ERIC1
Frequently bought together:
Description
I抗体名: | TACC3 Rabbit mAb |
抗体コード: | CAB19617 |
サイズ: | 20uL, 50uL, 100uL |
同義語: | ERIC-1, ERIC1 |
申し込み: | WB, IHC, IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human TACC3 |
申し込み: | WB, IHC, IF |
推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T |
免疫原: | A synthesized peptide derived from human TACC3 |
精製方法: | Affinity purification |
保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 10460 |
Uniprot: | Q9Y6A5 |
計算された分子量: | 140kDa |
観察された分子量: | 140KDa |
UniProt Protein Function: | TACC3: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May be involved in the control of cell growth and differentiation. May contribute to cancer. Interacts with microtubules. Interacts with CCDC100/CEP120. The coiled coil C-terminus region interacts with AH receptor nuclear translocator protein (ARNT) and ARNT2. Interacts with GCN5L2 and PCAF. Up-regulated in various cancer cell lines. Belongs to the TACC family. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 4p16.3 Cellular Component: centrosome; cytoplasm Molecular Function:protein domain specific binding; protein binding Biological Process: regulation of microtubule-based process; cell proliferation; cytoplasmic sequestering of transcription factor; astral microtubule organization and biogenesis; neurogenesis; regulation of cell cycle; response to hypoxia; hemopoiesis; microtubule cytoskeleton organization and biogenesis; cerebral cortex development; interkinetic nuclear migration Disease: Bladder Cancer |
NCBI Summary: | The function of this gene has not yet been determined; however, it is speculated that it may be involved in cell growth and differentiation. Expression of this gene is up-regulated in some cancer cell lines, and in embryonic day 15 in mice. [provided by RefSeq] |
UniProt Code: | Q9Y6A5 |
NCBI GenInfo Identifier: | 5454102 |
NCBI Gene ID: | 10460 |
NCBI Accession: | NP_006333.1 |
UniProt Related Accession: | Q2NKK4,Q8IX09,Q9Y6A5 |
Molecular Weight: | 90,522 Da |
NCBI Full Name: | transforming acidic coiled-coil-containing protein 3 |
NCBI Synonym Full Names: | transforming, acidic coiled-coil containing protein 3 |
NCBI Official Symbol: | TACC3 |
NCBI Official Synonym Symbols: | ERIC1; ERIC-1; MGC117382; MGC133242 |
NCBI Protein Information: | transforming acidic coiled-coil-containing protein 3; OTTHUMP00000113796 |
UniProt Protein Name: | Transforming, acidic coiled-coil containing protein 3 |
Protein Family: | Transforming acidic coiled-coil-containing protein |
UniProt Gene Name: | TACC3 |
UniProt Entry Name: | Q2NKK4_HUMAN |