Anti-SLC5A2 Antibody (CAB20271)
- SKU:
- CAB20271
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SGLT2
Frequently bought together:
Description
| 抗体名: | SLC5A2 Rabbit pAb |
| 抗体コード: | CAB20271 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | SGLT2 |
| 申し込み: | WB, IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human SLC5A2. |
| 申し込み: | WB, IHC |
| 推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, Jurkat, Mouse heart, Rat brain |
| 免疫原: | Recombinant protein of human SLC5A2. |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 6524 |
| Uniprot: | P31639 |
| 観察された分子量: | 70KDa |
| UniProt Protein Function: | SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. Protein type: Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: plasma membrane; integral to membrane Molecular Function: low-affinity glucose:sodium symporter activity Biological Process: transport; carbohydrate metabolic process; sodium ion transport; glucose transport; transmembrane transport Disease: Renal Glucosuria |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015] |
| UniProt Code: | P31639 |
| NCBI GenInfo Identifier: | 4507033 |
| NCBI Gene ID: | 6524 |
| NCBI Accession: | NP_003032.1 |
| UniProt Secondary Accession: | P31639,A2RRD2 |
| UniProt Related Accession: | P31639 |
| Molecular Weight: | |
| NCBI Full Name: | sodium/glucose cotransporter 2 |
| NCBI Synonym Full Names: | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| NCBI Official Symbol: | SLC5A2 |
| NCBI Official Synonym Symbols: | SGLT2 |
| NCBI Protein Information: | sodium/glucose cotransporter 2 |
| UniProt Protein Name: | Sodium/glucose cotransporter 2 |
| UniProt Synonym Protein Names: | Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2 |
| Protein Family: | |
| UniProt Gene Name: | SLC5A2 |
| UniProt Entry Name: | SC5A2_HUMAN |
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