The KMT1B/SUV39H2 Monoclonal Antibody (CAB3705) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, is able to detect KMT1B/SUV39H2 in human samples, making it ideal for use in Western blot applications.KMT1B/SUV39H2 is a histone methyltransferase that is involved in the regulation of chromatin structure and gene silencing. Dysregulation of KMT1B/SUV39H2 has been implicated in various diseases, including cancer and neurological disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
KMT1B/SUV39H2 Monoclonal Antibody
SKU:
CAB3705
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC0829
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
KMT1B, KMT1B / SUV39H2
Positive Sample:
HeLa, PC-3
Cellular Localization:
Nucleoplasm, Nucleus.
Calculated MW:
47kDa
Observed MW:
45kDa
Enables S-adenosyl-L-methionine binding activity; histone methyltransferase activity (H3-K9 specific); and zinc ion binding activity. Involved in chromatin assembly or disassembly and chromatin remodeling. Acts upstream of or within cellular response to hypoxia and negative regulation of transcription by RNA polymerase II. Located in chromatin.
Purification Method
Affinity purification
Gene ID
79723
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using KMT1B / SUV39H2 Rabbit mAb (CAB3705) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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