Anti-Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (CAB3687)
- SKU:
- CAB3687
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GC-S-beta-1
- Synonyms:
- GC-SB3
- Synonyms:
- GUC1B3
- Synonyms:
- GUCB3
- Synonyms:
- GUCSB3
- Synonyms:
- GUCY1B1
Frequently bought together:
Description
I抗体名: | Guanylyl Cyclase beta 1 (GUCY1B3) Rabbit mAb |
抗体コード: | CAB3687 |
サイズ: | 20uL, 50uL, 100uL |
同義語: | GC-S-beta-1, GC-SB3, GUC1B3, GUCB3, GUCSB3, GUCY1B1 |
申し込み: | WB, IHC, IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human Guanylyl Cyclase beta 1 (GUCY1B3) (GUCY1B3) |
申し込み: | WB, IHC, IF |
推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, Mouse lung, Mouse brain, Mouse heart, Rat brain |
免疫原: | A synthesized peptide derived from human Guanylyl Cyclase beta 1 (GUCY1B3) (GUCY1B3) |
精製方法: | Affinity purification |
保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 2983 |
Uniprot: | Q02153 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 71kDa |
観察された分子量: | 71kDa |
UniProt Protein Function: | GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing |
UniProt Protein Details: | Protein type:Receptor, misc.; Guanylyl cyclase; Lyase; Nucleotide Metabolism - purine; EC 4.6.1.2 Chromosomal Location of Human Ortholog: 4q31.3-q33 Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm Molecular Function:guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; Hsp90 protein binding; receptor activity Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction |
NCBI Summary: | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
UniProt Code: | Q02153 |
NCBI GenInfo Identifier: | 399328 |
NCBI Gene ID: | 2983 |
NCBI Accession: | Q02153.1 |
UniProt Secondary Accession: | Q02153,Q86WY5, B7Z426, |
UniProt Related Accession: | Q02153 |
Molecular Weight: | 619 |
NCBI Full Name: | Guanylate cyclase soluble subunit beta-1 |
NCBI Synonym Full Names: | guanylate cyclase 1, soluble, beta 3 |
NCBI Official Symbol: | GUCY1B3 |
NCBI Official Synonym Symbols: | GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1 |
NCBI Protein Information: | guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3 |
UniProt Protein Name: | Guanylate cyclase soluble subunit beta-1 |
UniProt Synonym Protein Names: | Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit |
Protein Family: | Guanylate cyclase soluble |
UniProt Gene Name: | GUCY1B3 |
UniProt Entry Name: | GCYB1_HUMAN |