Anti-Glycerol kinase (GK) Antibody (CAB19221)
- SKU:
- CAB19221
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GK
- Synonyms:
- GK1
- Synonyms:
- GKD
- Synonyms:
- glycerol kinase
Frequently bought together:
Description
| 抗体名: | Glycerol kinase (GK) Rabbit mAb |
| 抗体コード: | CAB19221 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | GK, GK1, GKD, glycerol kinase |
| 申し込み: | WB, IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human Glycerol kinase (GK) (GK). |
| 申し込み: | WB, IHC |
| 推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, U-87MG, Mouse testis, Rat liver, Rat testis, Rat kidney |
| 免疫原: | Recombinant protein of human Glycerol kinase (GK) (GK). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 2710 |
| Uniprot: | P32189 |
| セルラーロケーション: | Cytoplasm, Cytoplasmic side, Mitochondrion outer membrane, Peripheral membrane protein |
| 計算された分子量: | 50kDa |
| 観察された分子量: | 57KDa |
| UniProt Protein Function: | GLPK: Key enzyme in the regulation of glycerol uptake and metabolism. Defects in GK are the cause of GK deficiency (GKD). This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only. Belongs to the FGGY kinase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.7.1.30; Lipid Metabolism - glycerolipid; Mitochondrial; Kinase, other Chromosomal Location of Human Ortholog: Xp21.3 Cellular Component: mitochondrial outer membrane; cytosol; nucleus Molecular Function:glycerol kinase activity; protein binding; ATP binding Biological Process: triacylglycerol metabolic process; glycerol metabolic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; glucose homeostasis; phosphorylation; glycerol-3-phosphate biosynthetic process; glycerol catabolic process Disease: Glycerol Kinase Deficiency |
| NCBI Summary: | The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| UniProt Code: | P32189 |
| NCBI GenInfo Identifier: | 205830913 |
| NCBI Gene ID: | 2710 |
| NCBI Accession: | P32189.3 |
| UniProt Secondary Accession: | P32189,Q6IQ27, Q8IVR5, Q9UMP0, Q9UMP1, A6NJP5, B2R833 |
| UniProt Related Accession: | P32189 |
| Molecular Weight: | 58,141 Da |
| NCBI Full Name: | Glycerol kinase |
| NCBI Synonym Full Names: | glycerol kinase |
| NCBI Official Symbol: | GK |
| NCBI Official Synonym Symbols: | GK1; GKD |
| NCBI Protein Information: | glycerol kinase; ATP:glycerol 3-phosphotransferase; glycerokinase |
| UniProt Protein Name: | Glycerol kinase |
| UniProt Synonym Protein Names: | ATP:glycerol 3-phosphotransferase |
| Protein Family: | Glycerol kinase |
| UniProt Gene Name: | GK |
| UniProt Entry Name: | GLPK_HUMAN |
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