Anti-GABA A Receptor beta 1 (GABRB1) Antibody (CAB19681)

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SKU:
CAB19681
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
EIEE45
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Description

抗体名:GABA A Receptor beta 1 (GABRB1) Rabbit mAb
抗体コード:CAB19681
サイズ:20uL, 50uL, 100uL
同義語:EIEE45
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:A synthesized peptide derived from human GABA A Receptor beta 1 (GABRB1) (GABRB1)
申し込み:WB
推奨される希釈:WB 1:500 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:SH-SY5Y, Mouse spinal cord, Mouse brain, Rat brain
免疫原:A synthesized peptide derived from human GABA A Receptor beta 1 (GABRB1) (GABRB1)
精製方法:Affinity purification
保管所:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:2560
Uniprot:P18505
計算された分子量:48kDa
観察された分子量:54KDa
UniProt Protein Function:GABRB1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
UniProt Protein Details:

Protein type:Channel, chloride; Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, ion channel; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 4p12

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction

Molecular Function:chloride channel activity; GABA-A receptor activity; ligand-gated ion channel activity; extracellular ligand-gated ion channel activity

Biological Process: synaptic transmission; transport; ion transport; signal transduction; transmembrane transport

NCBI Summary:The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
UniProt Code:P18505
NCBI GenInfo Identifier:194097327
NCBI Gene ID:2560
NCBI Accession:NP_000803.2
UniProt Related Accession:P18505
Molecular Weight:~ 54kDa
NCBI Full Name:gamma-aminobutyric acid receptor subunit beta-1
NCBI Synonym Full Names:gamma-aminobutyric acid type A receptor subunit beta1
NCBI Official Symbol:GABRB1  
NCBI Official Synonym Symbols:EIEE45  
NCBI Protein Information:gamma-aminobutyric acid receptor subunit beta-1
UniProt Protein Name:Gamma-aminobutyric acid receptor subunit beta-1
UniProt Synonym Protein Names:GABA(A) receptor subunit beta-1
UniProt Gene Name:GABRB1  
UniProt Entry Name:GBRB1_HUMAN
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