Anti-DCR2 Antibody (CAB3581)
- SKU:
- CAB3581
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD264
- Synonyms:
- DCR2
- Synonyms:
- TRAIL-R4
- Synonyms:
- TRAILR4
- Synonyms:
- TRUNDD
Frequently bought together:
Description
| I抗体名: | DCR2 Rabbit mAb |
| 抗体コード: | CAB3581 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD |
| 申し込み: | WB, IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human DCR2 |
| 申し込み: | WB, IHC |
| 推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Mouse kidney, Rat liver, Rat kidney |
| 免疫原: | A synthesized peptide derived from human DCR2 |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 8793 |
| Uniprot: | Q9UBN6 |
| 計算された分子量: | 36kDa |
| 観察された分子量: | 45-60KDa |
| UniProt Protein Function: | TRAIL-R4: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 8p21 Cellular Component: integral to membrane Molecular Function:transmembrane receptor activity; TRAIL binding Biological Process: apoptosis; signal transduction; negative regulation of apoptosis |
| NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UBN6 |
| NCBI GenInfo Identifier: | 18203495 |
| NCBI Gene ID: | 8793 |
| NCBI Accession: | Q9UBN6.1 |
| UniProt Secondary Accession: | Q9UBN6,Q9Y6Q4, B2R8W0, |
| UniProt Related Accession: | Q9UBN6 |
| Molecular Weight: | 41,823 Da |
| NCBI Full Name: | Tumor necrosis factor receptor superfamily member 10D |
| NCBI Synonym Full Names: | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| NCBI Official Symbol: | TNFRSF10D |
| NCBI Official Synonym Symbols: | DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4 |
| NCBI Protein Information: | tumor necrosis factor receptor superfamily member 10D; TRAIL receptor 4; decoy receptor 2; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4 |
| UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 10D |
| UniProt Synonym Protein Names: | Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain; CD_antigen: CD264 |
| Protein Family: | Tumor necrosis factor receptor superfamily |
| UniProt Gene Name: | TNFRSF10D |
| UniProt Entry Name: | TR10D_HUMAN |
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