Description
| 抗体名: | TACC3 Antibody |
| 抗体コード: | PACO01579 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| 反応性: | Human, Mouse |
| 免疫原: | synthesized peptide derived from the C-terminal region of human TACC3. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | TACC3; ERIC1; Transforming acidic coiled-coil-containing protein 3; ERIC-1 |
| UniProt Protein Function: | TACC3: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May be involved in the control of cell growth and differentiation. May contribute to cancer. Interacts with microtubules. Interacts with CCDC100/CEP120. The coiled coil C-terminus region interacts with AH receptor nuclear translocator protein (ARNT) and ARNT2. Interacts with GCN5L2 and PCAF. Up-regulated in various cancer cell lines. Belongs to the TACC family. |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 4p16.3 Cellular Component: centrosome; cytoplasm Molecular Function:protein domain specific binding; protein binding Biological Process: regulation of microtubule-based process; cell proliferation; cytoplasmic sequestering of transcription factor; astral microtubule organization and biogenesis; neurogenesis; regulation of cell cycle; response to hypoxia; hemopoiesis; microtubule cytoskeleton organization and biogenesis; cerebral cortex development; interkinetic nuclear migration Disease: Bladder Cancer |
| NCBI Summary: | The function of this gene has not yet been determined; however, it is speculated that it may be involved in cell growth and differentiation. Expression of this gene is up-regulated in some cancer cell lines, and in embryonic day 15 in mice. [provided by RefSeq] |
| UniProt Code: | Q9Y6A5 |
| NCBI GenInfo Identifier: | 5454102 |
| NCBI Gene ID: | 10460 |
| NCBI Accession: | NP_006333.1 |
| UniProt Related Accession: | Q2NKK4,Q8IX09,Q9Y6A5 |
| Molecular Weight: | 90,522 Da |
| NCBI Full Name: | transforming acidic coiled-coil-containing protein 3 |
| NCBI Synonym Full Names: | transforming, acidic coiled-coil containing protein 3 |
| NCBI Official Symbol: | TACC3 |
| NCBI Official Synonym Symbols: | ERIC1; ERIC-1; MGC117382; MGC133242 |
| NCBI Protein Information: | transforming acidic coiled-coil-containing protein 3; OTTHUMP00000113796 |
| UniProt Protein Name: | Transforming, acidic coiled-coil containing protein 3 |
| Protein Family: | Transforming acidic coiled-coil-containing protein |
| UniProt Gene Name: | TACC3 |
| UniProt Entry Name: | Q2NKK4_HUMAN |
