SENP5 Antibody (PACO13604)
- SKU:
- PACO13604
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SENP5 Antibody (PACO13604) |
抗体コード: | PACO13604 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human SENP5-Specific |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | SUMO1/sentrin specific peptidase 5;SENP5;DKFZp564O1016;FLJ42398;MGC27076 ; |
UniProt Protein Function: | SENP5: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. Belongs to the peptidase C48 family. |
UniProt Protein Details: | Protein type:Nucleolus; Protease; EC 3.4.22.68 Chromosomal Location of Human Ortholog: 3q29 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus Molecular Function:endopeptidase activity; protein binding; SUMO-specific protease activity Biological Process: protein desumoylation; protein sumoylation |
NCBI Summary: | The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009] |
UniProt Code: | Q96HI0 |
NCBI GenInfo Identifier: | 296452962 |
NCBI Gene ID: | 205564 |
NCBI Accession: | Q96HI0.3 |
UniProt Secondary Accession: | Q96HI0,Q96SA5, B4DY82, |
UniProt Related Accession: | Q96HI0 |
Molecular Weight: | 81,310 Da |
NCBI Full Name: | Sentrin-specific protease 5 |
NCBI Synonym Full Names: | SUMO1/sentrin specific peptidase 5 |
NCBI Official Symbol: | SENP5 |
NCBI Protein Information: | sentrin-specific protease 5 |
UniProt Protein Name: | Sentrin-specific protease 5 |
UniProt Synonym Protein Names: | Sentrin/SUMO-specific protease SENP5 |
Protein Family: | Sentrin-specific protease |
UniProt Gene Name: | SENP5 |
UniProt Entry Name: | SENP5_HUMAN |