Phospho-MYL12A/MYL12B/MYL9 (T17/S18) Antibody (PACO03360)

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SKU:
PACO03360
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Application:
ELISA
Application:
IHC
Antibody type:
Polyclonal
Conjugation:
Unconjugated
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Phospho-MYL12A/MYL12B/MYL9 (T17/S18) Antibody
抗体コード:PACO03360
サイズ:50ug
宿主種:Rabbit
申し込み:ELISA, IHC
推奨される希釈:IHC:1:100-1:300
反応性:Human, Mouse, Rat
免疫原:synthesized peptide derived from human MLC-2 around the phosphorylation site of T17/S18.
憲法:Liquid
ストレージバッファ:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
精製方法:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
抗体のクローン性:Polyclonal
アイソタイプ:IgG
Conjugate:Non-conjugated
シノニム:MYL12A; MLCB; MRLC3; RLC; Myosin regulatory light chain 12A; MLC-2B; Myosin RLC; Myosin regulatory light chain 2; nonsarcomeric; Myosin regulatory light chain MRLC3; MYL12B; MRLC2; MYLC2B; Myosin regulatory light chain 12B; MLC-2A; MLC-2; M
UniProt Protein Function:MRLC3: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Myosin is an hexamer of 2 heavy chains and 4 light chains.
UniProt Protein Details:

Protein type:Contractile

Chromosomal Location of Human Ortholog: 18p11.31

Cellular Component: myosin II complex; stress fiber; cytosol; Z disc

Molecular Function:protein binding; glutamate receptor binding; calcium ion binding

Biological Process: axon guidance; regulation of cell shape; ephrin receptor signaling pathway

NCBI Summary:This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014]
UniProt Code:P19105
NCBI GenInfo Identifier:127169
NCBI Gene ID:10627
NCBI Accession:P19105.2
UniProt Secondary Accession:P19105,Q53X45,
UniProt Related Accession:P19105
Molecular Weight:171
NCBI Full Name:Myosin regulatory light chain 12A
NCBI Synonym Full Names:myosin, light chain 12A, regulatory, non-sarcomeric
NCBI Official Symbol:MYL12A  
NCBI Official Synonym Symbols:MLCB; MRCL3; MRLC3; MYL2B; MLC-2B; HEL-S-24  
NCBI Protein Information:myosin regulatory light chain 12A; myosin RLC; myosin regulatory light chain 3; epididymis secretory protein Li 24; myosin regulatory light chain MRLC3; myosin regulatory light chain 2, nonsarcomeric; myosin, light polypeptide, regulatory, non-sarcomeric
UniProt Protein Name:Myosin regulatory light chain 12A
UniProt Synonym Protein Names:Epididymis secretory protein Li 24; HEL-S-24; MLC-2B; Myosin RLC; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain MRLC3
Protein Family:C-type mannose receptor
UniProt Gene Name:MYL12A  
UniProt Entry Name:ML12A_HUMAN
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