NFKBID Antibody (PACO13938)
- SKU:
- PACO13938
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NFKBID Antibody (PACO13938) |
抗体コード: | PACO13938 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Fusion protein of human NFKBID |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 10+12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, 231 cells, Primary antibody: PACO13938(NFKBID Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO13938(NFKBID Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.I κ BNS, the nuclear I κ B-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.I κ BNS has been identified as a member of the I κ B family of NF- κ B inhibitors, which undergoes induction upon TCR signaling. I κ BNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine. |
シノニム: | nuclear factor of κ light polypeptide gene enhancer in B-cells inhibitor, delta |
UniProt Protein Function: | NFKBID: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR- induced negative selection of thymocytes. Belongs to the NF-kappa-B inhibitor family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: nucleus Molecular Function:NF-kappaB binding Biological Process: inhibition of NF-kappaB transcription factor; negative regulation of T cell differentiation in the thymus; negative regulation of I-kappaB kinase/NF-kappaB cascade; inflammatory response |
UniProt Code: | Q8NI38 |
NCBI GenInfo Identifier: | 74751323 |
NCBI Gene ID: | 84807 |
NCBI Accession: | Q8NI38.1 |
UniProt Secondary Accession: | Q8NI38,Q8NI39, Q9BRG9, |
UniProt Related Accession: | Q8NI38 |
Molecular Weight: | 150 |
NCBI Full Name: | NF-kappa-B inhibitor delta |
NCBI Synonym Full Names: | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta |
NCBI Official Symbol: | NFKBID |
NCBI Official Synonym Symbols: | TA-NFKBH; IkappaBNS |
NCBI Protein Information: | NF-kappa-B inhibitor delta; ikB-delta; ikappaBdelta; I-kappa-B-delta; T-cell activation NFKB-like protein |
UniProt Protein Name: | NF-kappa-B inhibitor delta |
UniProt Synonym Protein Names: | I-kappa-B-delta; IkB-delta; IkappaBdelta; IkappaBNS; T-cell activation NFKB-like protein; TA-NFKBH |
Protein Family: | NF-kappa-B inhibitor |
UniProt Gene Name: | NFKBID |
UniProt Entry Name: | IKBD_HUMAN |