MYRF Antibody (PACO54238)
- SKU:
- PACO54238
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MYRF Antibody (PACO54238) |
抗体コード: | PACO54238 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Myelin regulatory factor protein (843-1004AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: MYRF antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 125, 121 kDa. Observed band size: 125 kDa. | |
Immunofluorescence staining of A549 cells with PACO54238 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human lung tissue using PACO54238 at dilution of 1:100. |
バックグラウンド: | Myelin regulatory factor: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes. |
シノニム: | Myelin regulatory factor (EC 3.4) (Myelin gene regulatory factor) [Cleaved into: Myelin regulatory factor, N-terminal; Myelin regulatory factor, C-terminal], MYRF, C11orf9 KIAA0954 MRF |
UniProt Protein Function: | Myelin regulatory factor: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). |
NCBI Summary: | This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
UniProt Code: | Q9Y2G1 |
NCBI GenInfo Identifier: | 188528652 |
NCBI Gene ID: | 745 |
NCBI Accession: | NP_001120864.1 |
UniProt Secondary Accession: | Q9Y2G1,O43582, Q9P1Q6, |
UniProt Related Accession: | Q9Y2G1 |
Molecular Weight: | 120,225 Da |
NCBI Full Name: | myelin regulatory factor isoform 2 |
NCBI Synonym Full Names: | myelin regulatory factor |
NCBI Official Symbol: | MYRF |
NCBI Official Synonym Symbols: | MRF; Ndt80; pqn-47; C11orf9 |
NCBI Protein Information: | myelin regulatory factor |
UniProt Protein Name: | Myelin regulatory factor |
UniProt Synonym Protein Names: | Myelin gene regulatory factor |
UniProt Gene Name: | MYRF |
Antibodies |
Anti-MYRF Antibody (CAB16355) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |