MPHOSPH8 Antibody (PACO10553)
- SKU:
- PACO10553
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MPHOSPH8 Antibody (PACO10553) |
抗体コード: | PACO10553 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human MPHOSPH8 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | M-phase phosphoprotein 8;MPHOSPH8;FLJ35237;HSMPP8;TWA3;mpp8 ; |
UniProt Protein Function: | Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416). Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3 (PubMed:26022416). Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592). Mediates down-regulation of CDH1 expression (PubMed:20871592). |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q99549 |
NCBI GenInfo Identifier: | 41055989 |
NCBI Gene ID: | 54737 |
NCBI Accession: | NP_059990.2 |
UniProt Secondary Accession: | Q99549,Q5JPE5, Q5JTQ0, Q86TK3, Q96MK4, Q9BTP1, B7Z6F9 |
UniProt Related Accession: | Q99549 |
Molecular Weight: | 94 |
NCBI Full Name: | M-phase phosphoprotein 8 |
NCBI Synonym Full Names: | M-phase phosphoprotein 8 |
NCBI Official Symbol: | MPHOSPH8 |
NCBI Official Synonym Symbols: | TWA3; mpp8; HSMPP8 |
NCBI Protein Information: | M-phase phosphoprotein 8 |
UniProt Protein Name: | M-phase phosphoprotein 8 |
UniProt Synonym Protein Names: | Two hybrid-associated protein 3 with RanBPM |
Protein Family: | |
UniProt Gene Name: | MPHOSPH8 |
UniProt Entry Name: |