Description
| 抗体名: | JCHAIN Antibody (PACO45225) |
| 抗体コード: | PACO45225 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Immunoglobulin J chain protein (23-159AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO45225 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO45225 at dilution of 1:100. |
| バックグラウンド: | Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. |
| シノニム: | Immunoglobulin J chain (Joining chain of multimeric IgA and IgM), JCHAIN, IGCJ IGJ |
| UniProt Protein Function: | IGJ: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q21 Cellular Component: extracellular region; extracellular space Molecular Function:IgA binding; peptidoglycan binding; phosphatidylcholine binding; protein homodimerization activity; single-stranded DNA binding Biological Process: adaptive immune response; antibacterial humoral response; glomerular filtration; innate immune response; positive regulation of protein oligomerization; receptor-mediated endocytosis; retinal homeostasis |
| UniProt Code: | P01591 |
| NCBI GenInfo Identifier: | 261260100 |
| NCBI Gene ID: | 3512 |
| NCBI Accession: | P01591.4 |
| UniProt Related Accession: | P01591 |
| Molecular Weight: | 18,099 Da |
| NCBI Full Name: | Immunoglobulin J chain |
| NCBI Synonym Full Names: | joining chain of multimeric IgA and IgM |
| NCBI Official Symbol: | JCHAIN |
| NCBI Official Synonym Symbols: | IGJ; JCH; IGCJ |
| NCBI Protein Information: | immunoglobulin J chain |
| UniProt Protein Name: | Immunoglobulin J chain |
| UniProt Synonym Protein Names: | Joining chain of multimeric IgA and IgM |
| UniProt Gene Name: | JCHAIN |
| UniProt Entry Name: | IGJ_HUMAN |
