CORO1A Antibody (PACO48302)
- SKU:
- PACO48302
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CORO1A Antibody (PACO48302) |
抗体コード: | PACO48302 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Coronin-1A protein (363-432AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse lung tissue. All lanes: CORO1A antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO48302 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO48302 at dilution of 1:100. |
バックグラウンド: | May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. |
シノニム: | Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO), CORO1A, CORO1 |
UniProt Protein Function: | coronin 1A: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. Belongs to the WD repeat coronin family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: actin filament; axon; cortical actin cytoskeleton; cytoplasm; early endosome; immunological synapse; intercellular junction; lamellipodium; membrane; nucleus; phagocytic cup; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; protein complex Molecular Function:actin binding; actin filament binding; actin monomer binding; cytoskeletal protein binding; myosin heavy chain binding; phosphoinositide 3-kinase binding; protein binding; protein C-terminus binding; protein homodimerization activity Biological Process: actin cytoskeleton organization and biogenesis; actin filament organization; calcium ion transport; cell motility; cell-substrate adhesion; formation of immunological synapse; homeostasis of number of cells within a tissue; innate immune response; leukocyte chemotaxis; natural killer cell degranulation; negative regulation of actin nucleation; negative regulation of neuron apoptosis; negative regulation of vesicle fusion; phagocytosis; phagolysosome formation; positive chemotaxis; positive regulation of cell migration; positive regulation of T cell proliferation; regulation of actin cytoskeleton organization and biogenesis; regulation of cell shape; regulation of release of sequestered calcium ion into cytosol; T cell homeostasis; uropod organization and biogenesis Disease: Immunodeficiency 8 |
NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16. [provided by RefSeq, Sep 2010] |
UniProt Code: | P31146 |
NCBI GenInfo Identifier: | 1706004 |
NCBI Gene ID: | 11151 |
NCBI Accession: | P31146.4 |
UniProt Secondary Accession: | P31146,Q2YD73, B2RBL1, |
UniProt Related Accession: | P31146 |
Molecular Weight: | 51,026 Da |
NCBI Full Name: | Coronin-1A |
NCBI Synonym Full Names: | coronin 1A |
NCBI Official Symbol: | CORO1A |
NCBI Official Synonym Symbols: | p57; IMD8; TACO; CLABP; HCORO1; CLIPINA |
NCBI Protein Information: | coronin-1A |
UniProt Protein Name: | Coronin-1A |
UniProt Synonym Protein Names: | Coronin-like protein A; Clipin-A; Coronin-like protein p57; Tryptophan aspartate-containing coat protein; TACO |
Protein Family: | Coronin |
UniProt Gene Name: | CORO1A |
UniProt Entry Name: | COR1A_HUMAN |
Antibodies | ELISA Kits |
Anti-Coronin-1A Antibody (CAB9300) | Human Coronin-1A ELISA Kit |
CORO1A Antibody (PACO02400) | Human Coronin-1A (CORO1A) ELISA Kit |
CORO1A Antibody (PACO08536) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |