UniProt Protein Function: | Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability. |
NCBI Summary: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010] |
UniProt Code: | P56750 |
NCBI GenInfo Identifier: | 6912316 |
NCBI Gene ID: | 26285 |
NCBI Accession: | NP_036263.1 |
UniProt Secondary Accession: | P56750,Q3MJB5, Q6UY37, |
UniProt Related Accession: | P56750 |
Molecular Weight: | 25 kDa |
NCBI Full Name: | claudin-17 |
NCBI Synonym Full Names: | claudin 17 |
NCBI Official Symbol: | CLDN17 |
NCBI Protein Information: | claudin-17 |
UniProt Protein Name: | Claudin-17 |
Protein Family: | Claudin |
UniProt Gene Name: | CLDN17 |