C7 Antibody (PACO43133)
- SKU:
- PACO43133
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | C7 Antibody (PACO43133) |
抗体コード: | PACO43133 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Complement component C7 protein (22-270AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO43133 at dilution of 1:100. |
バックグラウンド: | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. |
シノニム: | Complement component C7, C7 |
UniProt Protein Function: | C7: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 5p13 Cellular Component: extracellular region; membrane attack complex Biological Process: complement activation; complement activation, alternative pathway; complement activation, classical pathway; cytolysis; innate immune response; regulation of complement activation Disease: Complement Component 7 Deficiency |
NCBI Summary: | C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008] |
UniProt Code: | P10643 |
NCBI GenInfo Identifier: | 61252057 |
NCBI Gene ID: | 730 |
NCBI Accession: | P10643.2 |
UniProt Secondary Accession: | P10643,Q6P3T5, Q92489, |
UniProt Related Accession: | P10643 |
Molecular Weight: | 93,518 Da |
NCBI Full Name: | Complement component C7 |
NCBI Synonym Full Names: | complement component 7 |
NCBI Official Symbol: | C7 |
NCBI Protein Information: | complement component C7 |
UniProt Protein Name: | Complement component C7 |
Protein Family: | Complement component |
UniProt Gene Name: | C7 |
UniProt Entry Name: | CO7_HUMAN |
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