Description
| 抗体名: | C7 Antibody (PACO43133) |
| 抗体コード: | PACO43133 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Complement component C7 protein (22-270AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO43133 at dilution of 1:100. |
| バックグラウンド: | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. |
| シノニム: | Complement component C7, C7 |
| UniProt Protein Function: | C7: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 5p13 Cellular Component: extracellular region; membrane attack complex Biological Process: complement activation; complement activation, alternative pathway; complement activation, classical pathway; cytolysis; innate immune response; regulation of complement activation Disease: Complement Component 7 Deficiency |
| NCBI Summary: | C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P10643 |
| NCBI GenInfo Identifier: | 61252057 |
| NCBI Gene ID: | 730 |
| NCBI Accession: | P10643.2 |
| UniProt Secondary Accession: | P10643,Q6P3T5, Q92489, |
| UniProt Related Accession: | P10643 |
| Molecular Weight: | 93,518 Da |
| NCBI Full Name: | Complement component C7 |
| NCBI Synonym Full Names: | complement component 7 |
| NCBI Official Symbol: | C7 |
| NCBI Protein Information: | complement component C7 |
| UniProt Protein Name: | Complement component C7 |
| Protein Family: | Complement component |
| UniProt Gene Name: | C7 |
| UniProt Entry Name: | CO7_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
