BPI Antibody (PACO48846)
- SKU:
- PACO48846
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BPI Antibody (PACO48846) |
抗体コード: | PACO48846 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Bactericidal permeability-increasing protein (149-362AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HEK293 whole cell lysate. All lanes: BPI antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 54 kDa. Observed band size: 54 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO48846 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |
シノニム: | Bactericidal permeability-increasing protein (BPI) (CAP 57), BPI |
UniProt Protein Function: | BPI: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. |
UniProt Protein Details: | Protein type:Cell surface; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20q11.23 Cellular Component: integral to plasma membrane Molecular Function:lipopolysaccharide binding Biological Process: negative regulation of interleukin-6 production; negative regulation of interleukin-8 production; negative regulation of macrophage activation; negative regulation of tumor necrosis factor production |
NCBI Summary: | This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has antimicrobial activity against gram-negative organisms. [provided by RefSeq, Nov 2014] |
UniProt Code: | P17213 |
NCBI GenInfo Identifier: | 215274242 |
NCBI Gene ID: | 671 |
NCBI Accession: | P17213.4 |
UniProt Secondary Accession: | P17213,Q1ZZU8, Q5JRW0, Q8IW58, Q9BYZ9, Q9H1L2, Q9H1M8 Q9H203, Q9UCT4, Q9UD65, B2RCY2, |
UniProt Related Accession: | P17213 |
Molecular Weight: | |
NCBI Full Name: | Bactericidal permeability-increasing protein |
NCBI Synonym Full Names: | bactericidal/permeability-increasing protein |
NCBI Official Symbol: | BPI |
NCBI Official Synonym Symbols: | rBPI; BPIFD1 |
NCBI Protein Information: | bactericidal permeability-increasing protein |
UniProt Protein Name: | Bactericidal permeability-increasing protein |
UniProt Synonym Protein Names: | CAP 57 |
Protein Family: | BPI fold-containing family |
UniProt Gene Name: | BPI |
UniProt Entry Name: | BPI_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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