Description
| 抗体名: | ZNF365 Antibody, FITC conjugated (PACO46696) |
| 抗体コード: | PACO46696 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Protein ZNF365 protein (241-401AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| シノニム: | Protein ZNF365 (DISC1-binding zinc-finger protein) (Protein su48), ZNF365, DBZ KIAA0844 |
| UniProt Protein Function: | Involved in the regulation of neurogenesis. Negatively regulates neurite outgrowth (PubMed:17389905). Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis. Involved in the positive regulation of oligodendrocyte differentiation during postnatal growth. Involved in dendritic arborization, morphogenesis of spine density dendrite, and establishment of postsynaptic dendrite density in cortical pyramidal neurons (). Involved in homologous recombination (HR) repair pathway. Required for proper resolution of DNA double-strand breaks (DSBs) by HR. Is required for recovery of stalled replication forks, and directly contributes to genomic stability. Interacts with PARP1 and mediates MRE11-dependent DNA end resection during replication fork recovery (PubMed:23966166). Contributes to genomic stability by preventing telomere dysfunction (PubMed:23776040). |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified. [provided by RefSeq, May 2010] |
| UniProt Code: | Q70YC5 |
| NCBI GenInfo Identifier: | 40789306 |
| NCBI Gene ID: | 22891 |
| NCBI Accession: | NP_955523 |
| UniProt Secondary Accession: | Q70YC5 |
| UniProt Related Accession: | Q70YC5,Q70YC4, Q70YC5 |
| Molecular Weight: | 51kDa |
| NCBI Full Name: | protein ZNF365 isoform C |
| NCBI Synonym Full Names: | zinc finger protein 365 |
| NCBI Official Symbol: | ZNF365 |
| NCBI Official Synonym Symbols: | UAN; Su48; ZNF365D |
| NCBI Protein Information: | protein ZNF365 |
| UniProt Protein Name: | Protein ZNF365 |
| UniProt Synonym Protein Names: | DISC1-binding zinc-finger protein |
| Protein Family: | Protein |
| UniProt Gene Name: | ZNF365 |
| UniProt Entry Name: |
