The ZFAND2B Polyclonal Antibody (PAC020946) is a valuable tool for studying the ZFAND2B protein, a regulator of gene expression and cell growth. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the ZFAND2B protein, researchers can easily detect and analyze its presence in various cell types, providing insights into its functions in molecular pathways related to cell proliferation and differentiation.ZFAND2B, a zinc finger, AN1-type domain-containing protein, is known to interact with transcription factors and chromatin modifiers, influencing gene expression and cellular processes.
Its involvement in cell growth regulation suggests potential implications in developmental biology, cancer research, and stem cell studies. By studying ZFAND2B activity, researchers can uncover its roles in controlling gene expression patterns and potentially develop new therapeutic strategies targeting this protein.
Antibody Name:
ZFAND2B Antibody (PACO20946)
Antibody SKU:
PACO20946
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human ZFAND2B
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane: Mouse brain tissue, Primary antibody: PACO20946(ZFAND2B Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute.
Background:
This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms:
zinc finger, AN1-type domain 2B
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
