Description
| 抗体名: | ZDHHC7 Antibody (PACO22492) |
| 抗体コード: | PACO22492 |
| サイズ: | 100ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthesized peptide derived from C-terminal of human ZDHHC7. |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HUVEC cells, using ZDHHC7 antibody. |
| バックグラウンド: | Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability By similarity. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors. |
| シノニム: | EC 2.3.1.-; ZDH7; ZDHC7; zinc finger 370; ZNF370 |
| UniProt Protein Function: | ZDHHC7: Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors. Belongs to the DHHC palmitoyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; EC 2.3.1.225; Transferase; Membrane protein, multi-pass; Palmitoyltransferase Chromosomal Location of Human Ortholog: 16q24.1 Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus Molecular Function:palmitoyltransferase activity Biological Process: peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine; protein palmitoylation |
| UniProt Code: | Q9NXF8 |
| NCBI GenInfo Identifier: | 116242853 |
| NCBI Gene ID: | 55625 |
| NCBI Accession: | Q9NXF8.2 |
| UniProt Secondary Accession: | Q9NXF8,Q8WV42, Q9NVD8, D3DUM1, |
| UniProt Related Accession: | Q9NXF8 |
| Molecular Weight: | 38,917 Da |
| NCBI Full Name: | Palmitoyltransferase ZDHHC7 |
| NCBI Synonym Full Names: | zinc finger DHHC-type containing 7 |
| NCBI Official Symbol: | ZDHHC7 |
| NCBI Official Synonym Symbols: | DHHC7; SERZ1; SERZ-B; ZNF370 |
| NCBI Protein Information: | palmitoyltransferase ZDHHC7 |
| UniProt Protein Name: | Palmitoyltransferase ZDHHC7 |
| UniProt Synonym Protein Names: | Zinc finger DHHC domain-containing protein 7 |
| Protein Family: | Palmitoyltransferase |
| UniProt Gene Name: | ZDHHC7 |
| UniProt Entry Name: | ZDHC7_HUMAN |
