Description
| 抗体名: | UNG Antibody, HRP conjugated (PACO47739) |
| 抗体コード: | PACO47739 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Uracil-DNA glycosylase protein (114-224AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | HRP |
| バックグラウンド: | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
| シノニム: | Uracil-DNA glycosylase (UDG) (EC 3.2.2.27), UNG, DGU UNG1 UNG15 |
| UniProt Protein Function: | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
| NCBI Summary: | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] |
| UniProt Code: | P13051 |
| NCBI GenInfo Identifier: | 6224979 |
| NCBI Gene ID: | 7374 |
| NCBI Accession: | NP_003353.1 |
| UniProt Secondary Accession: | P13051,O00637, O00719, Q93028, A8K5M6, B2R8Y1, |
| UniProt Related Accession: | P13051 |
| Molecular Weight: | |
| NCBI Full Name: | uracil-DNA glycosylase isoform UNG1 |
| NCBI Synonym Full Names: | uracil DNA glycosylase |
| NCBI Official Symbol: | UNG |
| NCBI Official Synonym Symbols: | DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15 |
| NCBI Protein Information: | uracil-DNA glycosylase |
| UniProt Protein Name: | Uracil-DNA glycosylase |
| Protein Family: | Probable uracil-DNA glycosylase |
| UniProt Gene Name: | UNG |