Description
| 抗体名: | TTI1 Antibody, HRP conjugated (PACO47495) |
| 抗体コード: | PACO47495 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human TELO2-interacting protein 1 homolog protein (692-858AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | HRP |
| バックグラウンド: | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. |
| シノニム: | TELO2-interacting protein 1 homolog (Protein SMG10), TTI1, KIAA0406 SMG10 |
| UniProt Protein Function: | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O43156 |
| NCBI GenInfo Identifier: | 743405613 |
| NCBI Gene ID: | 9675 |
| NCBI Accession: | |
| UniProt Secondary Accession: | O43156,Q5JX67, Q96A38, Q9BR47, Q9H4K0, D6W4K3 |
| UniProt Related Accession: | O43156 |
| Molecular Weight: | 122,069 Da |
| NCBI Full Name: | TELO2-interacting protein 1 homolog |
| NCBI Synonym Full Names: | TELO2 interacting protein 1 |
| NCBI Official Symbol: | TTI1 |
| NCBI Official Synonym Symbols: | smg-10; KIAA0406 |
| NCBI Protein Information: | TELO2-interacting protein 1 homolog |
| UniProt Protein Name: | TELO2-interacting protein 1 homolog |
| UniProt Synonym Protein Names: | Protein SMG10 |
| Protein Family: | TEL2-interacting protein |
| UniProt Gene Name: | TTI1 |
| UniProt Entry Name: | TTI1_HUMAN |
