Description
| 抗体名: | TSC22D1 Antibody (PACO12947) |
| 抗体コード: | PACO12947 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human TSC22D1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.320°C, Avoid freeze / thaw cycles. |
| 精製方法: | Protein A purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | 16kd; |
| UniProt Protein Function: | TSC22D1: Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter. Belongs to the TSC-22/Dip/Bun family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 13q14 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; positive regulation of apoptosis; positive regulation of cell proliferation; negative regulation of apoptosis |
| NCBI Summary: | This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q15714 |
| NCBI GenInfo Identifier: | 334302874 |
| NCBI Gene ID: | 8848 |
| NCBI Accession: | Q15714.3 |
| UniProt Secondary Accession: | Q15714,O00666, Q6AHX5, Q6IBU1, Q8NCN1, Q96JS5, B3KRL7 B9EGI0, |
| UniProt Related Accession: | Q15714 |
| Molecular Weight: | 58,859 Da |
| NCBI Full Name: | TSC22 domain family protein 1 |
| NCBI Synonym Full Names: | TSC22 domain family, member 1 |
| NCBI Official Symbol: | TSC22D1 |
| NCBI Official Synonym Symbols: | Ptg-2; TSC22; TGFB1I4 |
| NCBI Protein Information: | TSC22 domain family protein 1; cerebral protein 2; regulatory protein TSC-22; TGFbeta-stimulated clone 22; TGFB-stimulated clone 22 homolog; transcriptional regulator TSC-22; transforming growth factor beta-stimulated protein TSC-22; transforming growth factor beta-1-induced transcript 4 protein |
| UniProt Protein Name: | TSC22 domain family protein 1 |
| UniProt Synonym Protein Names: | Cerebral protein 2; Regulatory protein TSC-22; TGFB-stimulated clone 22 homolog; Transforming growth factor beta-1-induced transcript 4 protein |
| Protein Family: | TSC22 domain family protein |
| UniProt Gene Name: | TSC22D1 |
| UniProt Entry Name: | T22D1_HUMAN |
