Description
| 抗体名: | TRIP13 Antibody (PACO05744) |
| 抗体コード: | PACO05744 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:10000, WB:1:500-1:2000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthesized peptide derived from the C-terminal region of human TRIP13. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | TRIP13; PCH2; Pachytene checkpoint protein 2 homolog; Human papillomavirus type 16 E1 protein-binding protein; 16E1-BP; HPV16 E1 protein-binding protein; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-in |
| UniProt Protein Function: | TRIP13: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Belongs to the AAA ATPase family. PCH2 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: nucleus Molecular Function:identical protein binding; protein binding; transcription cofactor activity Biological Process: double-strand break repair; meiotic recombination; oogenesis; spermatogenesis; synaptonemal complex assembly; transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q15645 |
| NCBI GenInfo Identifier: | 85541056 |
| NCBI Gene ID: | 9319 |
| NCBI Accession: | Q15645.2 |
| UniProt Secondary Accession: | Q15645,O15324, C9K0T3, D3DTC0, |
| UniProt Related Accession: | Q15645 |
| Molecular Weight: | 22,084 Da |
| NCBI Full Name: | Pachytene checkpoint protein 2 homolog |
| NCBI Synonym Full Names: | thyroid hormone receptor interactor 13 |
| NCBI Official Symbol: | TRIP13 |
| NCBI Official Synonym Symbols: | 16E1BP |
| NCBI Protein Information: | pachytene checkpoint protein 2 homolog |
| UniProt Protein Name: | Pachytene checkpoint protein 2 homolog |
| UniProt Synonym Protein Names: | Human papillomavirus type 16 E1 protein-binding protein; 16E1-BP; HPV16 E1 protein-binding protein; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13 |
| UniProt Gene Name: | TRIP13 |
| UniProt Entry Name: | PCH2_HUMAN |
