Description
| 抗体名: | TRIM38 Antibody |
| 抗体コード: | PACO02323 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human, Mouse |
| 免疫原: | synthesized peptide derived from the Internal region of human RNF15. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | TRIM38; RNF15; RORET; Tripartite motif-containing protein 38; RING finger protein 15; Zinc finger protein RoRet |
| UniProt Protein Function: | TRIM38: E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. {ECO:0000269|PubMed:23056470} |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: cytosol Molecular Function:protein binding; signal transducer activity Biological Process: activation of NF-kappaB transcription factor; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; positive regulation of virion penetration into host cell |
| NCBI Summary: | This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012] |
| UniProt Code: | O00635 |
| NCBI GenInfo Identifier: | 21362879 |
| NCBI Gene ID: | 10475 |
| NCBI Accession: | O00635.1 |
| UniProt Secondary Accession: | O00635,B2R862, |
| UniProt Related Accession: | O00635 |
| Molecular Weight: | 53,416 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase TRIM38 |
| NCBI Synonym Full Names: | tripartite motif containing 38 |
| NCBI Official Symbol: | TRIM38 |
| NCBI Official Synonym Symbols: | RNF15; RORET |
| NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM38 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM38 |
| UniProt Synonym Protein Names: | RING finger protein 15; Tripartite motif-containing protein 38; Zinc finger protein RoRet |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | TRIM38 |
| UniProt Entry Name: | TRI38_HUMAN |
